Rotavirus vaccine

Rotavirus vaccine
Vaccine description
TargetRotavirus
Vaccine typeAttenuated
Clinical data
Trade namesRotarix, RotaTeq, others
AHFS/Drugs.comMonograph
MedlinePlusa607024
License data
Routes of
administration
By mouth
ATC code
Legal status
Legal status
  • US: ℞-only
  • In general: ℞ (Prescription only)
Identifiers
CAS Number
ChemSpider
  • none
KEGG
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The rotavirus vaccine is a vaccine used to protect against rotavirus infections, which are the leading cause of severe diarrhea among young children.[1] The vaccines prevent 15–34% of severe diarrhea in the developing world and 37–96% of the risk of death among young children due to severe diarrhea.[1] Immunizing babies decreases rates of disease among older people and those who have not been immunized.[2]

The World Health Organization (WHO) recommends that rotavirus vaccine be included in national routine vaccinations programs, especially in areas where the disease is common.[1] This should be done along with promoting breastfeeding, handwashing, clean water, and good sanitation.[1] It is given by mouth and requires two or three doses.[1] It should be given starting around six weeks of age.[1]

The vaccines are safe.[1] This includes their use in people with HIV/AIDS.[1] The vaccines are made from weakened rotavirus.[1]

The vaccine first became available in the United States in 2006.[3] It is on the World Health Organization's List of Essential Medicines.[4][5] As of 2013, there are two types of vaccine available globally, Rotarix and RotaTeq. Others are used in some countries.[1]

  1. ^ a b c d e f g h i j "Rotavirus vaccines. WHO position paper – January 2013". Relevé Épidémiologique Hebdomadaire. 88 (5): 49–64. February 2013. hdl:10665/242024. PMID 23424730.
  2. ^ Patel MM, Steele D, Gentsch JR, Wecker J, Glass RI, Parashar UD (January 2011). "Real-world impact of rotavirus vaccination". The Pediatric Infectious Disease Journal. 30 (1 Suppl): S1–S5. doi:10.1097/INF.0b013e3181fefa1f. PMID 21183833. S2CID 1893099.
  3. ^ "Rotavirus Vaccine Live Oral". The American Society of Health-System Pharmacists. Archived from the original on 22 December 2015. Retrieved 14 December 2015.
  4. ^ World Health Organization (2019). World Health Organization model list of essential medicines: 21st list 2019. Geneva: World Health Organization. hdl:10665/325771. WHO/MVP/EMP/IAU/2019.06. License: CC BY-NC-SA 3.0 IGO.
  5. ^ World Health Organization (2021). World Health Organization model list of essential medicines: 22nd list (2021). Geneva: World Health Organization. hdl:10665/345533. WHO/MHP/HPS/EML/2021.02.

Rotavirus vaccine

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